TSPDF correlates variation in local structure with kinetic behavior in amorphous pharmaceutical formulations
Many newly discovered, and possibly life-saving, drug compounds do not possess sufficient solubility or permeability in the digestive tract to make it to production status. Amorphous and nanocrystalline drug dispersions are being developed to overcome these issues but result in secondary issues with product stability. In a recent report, we have used the total scattering… Read More TSPDF correlates variation in local structure with kinetic behavior in amorphous pharmaceutical formulations