mPDF study of MnO highlighted by Brookhaven and Columbia

Billinge group members and collaborators recently conducted a detailed experimental and theoretical study of the magnetic interactions in the classic antiferromagnet MnO using magnetic pair distribution function (mPDF) analysis, resulting in a publication in Physical Review Letters (Frandsen et al, Phys. Rev. Lett. 116 197204, see here). This work, which has furthered the methodology of… Read More mPDF study of MnO highlighted by Brookhaven and Columbia

American Crystallography Association (ACA) 2016!

As the Billinge group looks forward to ACA 2016, we look back on the 2015 meeting! 1) Our very own, Simon Billinge and Pavol Juhas gave an exciting session on PDF application in pharmaceuticals. Specifically, how to use PDF analysis to determine solid-state structures of active pharmaceutical ingredients (APIs), for quality control, stability studies and… Read More American Crystallography Association (ACA) 2016!

Towards solution and refinement of organic crystal structures by fitting to the atomic pair distribution function

Analysis of atomic pair distribution function (PDF) has been widely applied and many wonderful results were obtained. However, studies on organic materials haven’t been practically feasible. The major difficulty is to maintain the molecular geometry during refinement. A method towards the solution and refinement of organic crystal structure are developed. By considering constraints on molecular… Read More Towards solution and refinement of organic crystal structures by fitting to the atomic pair distribution function

TSPDF correlates variation in local structure with kinetic behavior in amorphous pharmaceutical formulations

Many newly discovered, and possibly life-saving, drug compounds do not possess sufficient solubility or permeability in the digestive tract to make it to production status. Amorphous and nanocrystalline drug dispersions are being developed to overcome these issues but result in secondary issues with product stability. In a recent report, we have used the total scattering… Read More TSPDF correlates variation in local structure with kinetic behavior in amorphous pharmaceutical formulations

UNRAVELING THE CUPRATES: SCIENTISTS DEMONSTRATE LINK BETWEEN KEY COMPONENTS IN HIGH TEMPERATURE SUPERCONDUCTIVITY

A team led by researchers from Brookhaven National Laboratory (BNL) and Cornell University recently conducted a series of experiments which intimate a strong parental connection between the so called “electron density wave” phase and the “pseudo gap” phase, key components seen as responsible for superconductivity in high temperature superconductors. Led by Séamus Davis, a physicist… Read More UNRAVELING THE CUPRATES: SCIENTISTS DEMONSTRATE LINK BETWEEN KEY COMPONENTS IN HIGH TEMPERATURE SUPERCONDUCTIVITY

Kirsten accepts faculty position at University of Copenhagen

Last month we said goodbye to our favorite postdoc Kirsten Jensen. We are happy to report that she has accepted an Assistant Professorship in the Department of Chemistry at University of Copenhagen where she will be working on the synthesis and characterization of nanomaterials. During her time at Columbia, Kirsten focused on developing and using new thin-film… Read More Kirsten accepts faculty position at University of Copenhagen

PDF Detects Nanoparticles in Dilute Solutions

Many modern material systems contain heterogeneous mixtures of components, and it is important to be able to characterize the structures of the components in such mixtures. Working with low concentrations is often desirable, either to achieve the proper pharmacokinetic properties of a drug molecule or to prevent particle aggregation and settling. To study structure in… Read More PDF Detects Nanoparticles in Dilute Solutions

Chenyang Completes Ph.D

Congratulations to Chenyang for successfully defending his thesis!  In the first hour of his defense, which was open to the public, Chenyang delivered a riveting presentation on the structure and lattice dynamics of low-dimensional materials.  During his time with the Billinge group, his research focused primarily on combined atomic pair distribution function and inelastic x-ray scattering techniques to… Read More Chenyang Completes Ph.D

X-ray diffraction computed tomography reveals inner structure in batteries

Combining X-ray diffraction and PDF with computed tomography allows for spatially resolved structural analysis, which can help unravel structures in heterogeneous materials and map out the phases present in the system. We recently demonstrated this in a paper on complex structures in batteries, where we were able to map out the components in commercial AAA batteries… Read More X-ray diffraction computed tomography reveals inner structure in batteries